Treatments
Peri-oral Rejuvenation in Marylebone




One of the sure signs of ageing is the development of lines and wrinkles around the mouth. In youth, our skin is supple and quick to correct the creases caused by regular facial expressions such as smiling, but as elastin production falls away, lines and folds begin to form. Peri-oral rejuvenation revitalises the skin around the mouth to restore a smoother, more youthful complexion.
To book a Perioral Lines Rejuvenation consultation in Marylebone, or for more information, book online, get in touch via our contact form or call us on: 020 4539 8817



Anna Morselli
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The deepest and most persistent facial lines are dynamic – caused by repeated facial movements, and the mouth is the most mobile part of the face. Whether from smiling or pursing the lips, lines tend to develop above, below, and to the sides of the mouth.
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Peri-oral rejuvenation focuses on the area around the mouth, including lips, marionette lines, smoker’s lines, and corners of the mouth, to restore a smoother, more youthful appearance. Key benefits include:
Smoother fine lines around the mouth
Softens vertical “smoker’s lines” and superficial creases for a fresher look.
Restored volume and definition
Improves lost support around the mouth and helps define the lip border.
Lifted mouth corners
Can gently lift downturned corners of the mouth, reducing “sad” or tired expressions.
Improved balance and symmetry
Enhances harmony between the lips, mouth, and neighbouring facial features.
Reduced appearance of marionette lines
Helps lessen deep lines that run from the corners of the mouth toward the chin.
Natural-looking outcomes
When performed by a skilled practitioner, results are subtle and tailored to your facial anatomy.
Minimal downtime and quick results
Most patients see improvement immediately and can resume daily activities with little to no downtime.
Peri-oral rejuvenation is ideal for patients seeking natural enhancement of the mouth area without surgery, helping to refresh the lower face and restore youthful contours.
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The peri-oral zone includes several areas:
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Peri-oral rejuvenation makes use of carefully placed dermal filler injections, smoothing out dynamic lines and wrinkles around the mouth and adding volume to the lips if that is part of your treatment plan. We consult with you to understand your concerns and aesthetic goals, agreeing the right combination of dermal fillers for you. At Medisha Clinic, we are committed to delivering natural-looking results that bring out your natural beauty.
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Results last on average between 12 and 18 months and repeat treatments can turn a temporary improvement into a lasting enhancement of your appearance.
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Peri-oral rejuvenation at Medisha Clinic is performed by Dr Nish Shah, a medically qualified aesthetics doctor with extensive experience treating the delicate area around the mouth. Every treatment begins with a personalised consultation, allowing the approach to be carefully tailored to your facial structure, skin quality, and concerns such as fine lines, volume loss, or downturned mouth corners. Medisha Clinic is known for its natural-looking, conservative results, focusing on subtle rejuvenation rather than overfilling or altering expression. Patient safety, comfort, and aftercare are prioritised throughout, and the clinic’s discreet Mayfair, London location provides a professional and reassuring setting. With a strong reputation for high standards and consistently refined outcomes, Medisha Clinic is a trusted choice for peri-oral rejuvenation in London.
Dr Nish is a medically trained aesthetics practitioner with extensive training in non-surgical treatments including dermal fillers, Intraline PDO threads (lifting and rejuvenation), and anti-wrinkle injections.
Following his BSc degree in Biomedical Sciences from St George’s University of London, Dr Nish completed a Doctor of Medicine (MD) degree at All Saints University School of Medicine, before enjoying a wealth of clinical experience in the US, notably in Chicago.
Expertly trained by some of the best in the industry, Dr Nish developed his art when he underwent masterclass training in some of the most advanced treatments such as cheek augmentation, tear trough rejuvenation, non-surgical rhinoplasty, and chin/jaw augmentation.
Dr Nish is a brand ambassador and Key Opinion Leader for the world renowned Intraline – global leaders in the innovation of the highest quality PDO threads, dermal fillers, and skincare. He is a proud clinical trainer and lecturer at world-renowned Derma Medical academy – the UK’s number 1 aesthetics training provider; enabling him to share and teach his passion of aesthetics with other medical professionals.
Dr Nish is also the official trainer for Sunekos – provider of excellence in dermal biogenesis and winner of the Innovation and Pioneering Award at the Diamond Awards 2019.
At Medisha Clinic, you will always be treated by someone who is passionate about bringing their considerable knowledge and skills to bear to deliver the transformative, natural-looking results you are looking for.

Posted on Google Michelle KokTrustindex verifies that the original source of the review is Google. I would not trust anyone else except for Dr Nish in the industry. Genuinely puts the client’s wellbeing first and foremost, with excellent care and results.Posted on Google Julie KirkTrustindex verifies that the original source of the review is Google. ⭐⭐⭐⭐⭐ I had PDO threads done, and from the very beginning the experience was excellent. Dr Nish was very attentive and made me feel confident and relaxed, talking me through the entire procedure step by step. He was reassuring throughout, and the treatment itself was much more comfortable than I expected—it didn’t hurt at all. I went back for my 7-week review, and I’m absolutely over the moon with the results. I was already really happy, but Nish went the extra mile and added three more threads to achieve an even better outcome. I can’t recommend Dr Nish highly enough. His professionalism, care, and attention to detail are outstanding, and I’m so pleased with my results!Posted on Google KGTrustindex verifies that the original source of the review is Google. I couldn't be happier with my experience at Medisha Clinic. I had a PDO thread lift and botox, and the results have exceeded my expectations. What really stood out was Dr. Nish, who was incredibly patient and took the time to explain every step thoroughly so I knew exactly what to expect. Highly recommend to anyone considering these treatments!Posted on Google Nimisha MorjariaTrustindex verifies that the original source of the review is Google. Would 100% recommend Dr Nish! It was my first time to get any treatment done on my face, and he made me feel so comfortable and not nervous. Very knowledgeable and understood exactly what I wanted and gave amazing results! Will definitely be going back for other treatments!Posted on Google Beverley BlackmanTrustindex verifies that the original source of the review is Google. I cannot recommend Dr Nish highly enough. From the moment I visited his clinic, his professionalism and attention to detail were exceptional. After reviewing my photos, he immediately spotted subtle asymmetry in my cheeks and explained that most people are naturally uneven — reassuring me that even very small adjustments could make a noticeable difference. He also identified two other minor areas and corrected them with remarkable skill. I feel refreshed, notice the difference, and still look completely like myself — just more confident and balanced. What sets Dr Nish apart is his honesty and integrity. He told me, “I don’t expect to see you back for at least a year — you don’t need anything else.” That level of transparency and care is rare. Dr Nish is a true expert. The results are natural, and the experience was safe, comfortable, and confidence-boosting. I wouldn’t trust anyone else with my face.Posted on Google Ben BlairTrustindex verifies that the original source of the review is Google. I’ve never had anything done before, despite him probably having done this 1000 times - he’s very calming and assuring, really nice guy too, proper people’s person, the actual procedure itself felt like the smallest part because of how relaxed i was, 10/10 service, unreal results too.Posted on Google Andrea LibreaTrustindex verifies that the original source of the review is Google. Can I put 10 stars somewhere?? I rarely write reviews but this one had to be written. From the moment I walked into Dr Nish’s clinic, he greeted me with a big old smile like he had already known me for years. We chatted about the most random things and let me tell you, this man is funny and knows my whole life story at this point. I told him I wasn’t sure what I wanted done but that I was feeling old and tired looking. He went step by step looking at different parts of my face that bothered me and explained treatments that he recommended and what they would essentially do to each part of my face. I honestly felt like this was MY consultation and treatments that he had picked out specifically for MY face. It was a good feeling, a human feeling which is lacking in aesthetics sometimes. He brought all of that back to the consultation. I went ahead with all of the treatments he recommended and every result he explained came to life. I instantly saw a refreshed version of myself that I haven’t seen for years. I went from a tired mum who avoided mirrors to someone who was sending photos of my improved self in all of my girl chats. RUN don’t walk to Dr Nish’s clinic. He works wonders and I feel like I’ve walked out with a face that I now love and have made a new friend and new favorite clinician. Thank you Dr Nish!Posted on Google MGTrustindex verifies that the original source of the review is Google. Walking into this clinic & meeting Dr. Nish was like a breath of fresh air. I've finally met a doctor that I can have a conversation with. For those of you who are not familiar with cosmetic clinics, the doctors normally don't talk to you. Dr. Nish has excellent interpersonal skills. He is very skilled, polite, friendly and courteous. I achieved amazing results. I would not go anywhere else for treatments.Posted on Google lia jhalaTrustindex verifies that the original source of the review is Google. I had an amazing experience with this clinic, I’ve been wanting tear through filler for years but was too afraid o go through with it. I absolutely love my results ❤️Posted on Google Andrew ForsythTrustindex verifies that the original source of the review is Google. I went for a consultation a few months ago for PDO threads. Dr Nish explained everything in dept and answered all my questions, which put me at ease right away. I decided to go through with the PDO treatment and I'm extremely impressed with the results. The lift was instant and my skin is looking much more youthful. Dr Nish is a skilled practitioner, he's also very professional, knowledgeable and friendly. I would highly recommend to anyone!