PDO Thread Rejuvenation in Marylebone

Medisha Clinic | Aesthetic Clinic Mayfair

Restore Skin Health

PDO rejuvenation threads are placed at strategic points within the dermis to improve the quality and health of the skin. Once within the skin, they trigger the body’s healing processes, increasing collagen production, which restores the vitality and the appearance of tired or loose skin. Loss of collagen is one of the main factors in the appearance of ageing.

At Medisha Clinic in Mayfair, we only use the highest quality Intraline threads. Where some clinics stick to mono (singular) threads, Dr Nish also uses PDO triples and spirals for a significantly more enhanced result.

To book a PDO Rejuvenation Threads consultation in Marylebone, or for more information, get in touch via our contact form or call us on: 020 4539 8817

Medisha Clinic | Aesthetic Clinic Mayfair

Book your consultation with expert Dr Nish today.


Your PDO Thread Rejuvenation consultation in Mayfair

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  • We capture your needs, concerns and desired outcomes, consulting with you to draw up a personalised treatment plan.
  • We consider your medical history, ensuring you are a good candidate for the treatments you choose, including checking for allergies and other contraindications.
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Before and After

Dr Nish and his team are such lovely people and made me feel so comfortable at their clinic. Dr Nish understood my concerns and my results are so lovely. I feel so much more confident after the PDO treatment. Definitely the best clinic and would highly recommend!

Anna Morselli

FAQS about PDO Thread Rejuvenation


There are two types of PDO threads – rejuvenating threads and lifting threads, also known as cogs. At Medisha Clinic in Mayfair, we offer both treatments, but it’s important to understand that PDO Thread Rejuvenation is for optimal skin health rather than lifting. That said, the tightening effect on the skin might result in a small degree of lifting as a byproduct.


PDO Thread Rejuvenation has various benefits, including:

  • Skin tightening and contouring
  • Skin rejuvenation and increased collagen production
  • Reducing the signs of ageing such as fine lines and wrinkles


At our aesthetic clinic based in Mayfair, we will administer local anesthetic to block pain during the procedure to make this treatment as comfortable as possible. You might experience mild swelling, bruising, or soreness where the threads were placed for 3-7 days, which can be managed with over-the-counter medications.


Intraline PDO threads are made from the highest quality PDO (Polydioxanone) available – a colourless, biodegradable, synthetic polymer. Polydioxanone has been used in a surgical context for over 30 years, relied upon as sutures in both cardiovascular and orthopaedic procedures due to its robust, safe, and reliable performance. Intraline PDO threads are specially designed for precise insertion and effective dermal retention, providing optimal results.


Your body rightly perceives the threads as a foreign body, triggering the production of collagen – the protein that gives your skin its elasticity and structure.


PDO threads tighten and rejuvenate the skin, with results starting to show after 3-4 months and lasting 18-24 months. At Medisha Clinic in Mayfair, we are passionate about delivering natural-looking results.

Book your consultation with expert Dr Nish today.

About Dr Nish Shah

Dr Nish is a medically trained aesthetics practitioner with extensive training in non-surgical treatments including dermal fillers, Intraline PDO threads (lifting and rejuvenation), and anti-wrinkle injections.

Following his BSc degree in Biomedical Sciences from St George’s University of London, Dr Nish completed a Doctor of Medicine (MD) degree at All Saints University School of Medicine, before enjoying a wealth of clinical experience in the US, notably in Chicago.

Expertly trained by some of the best in the industry, Dr Nish developed his art when he underwent masterclass training in some of the most advanced treatments such as cheek augmentation, tear trough rejuvenation, non-surgical rhinoplasty, and chin/jaw augmentation.

Dr Nish is a brand ambassador and Key Opinion Leader for the world renowned Intraline – global leaders in the innovation of the highest quality PDO threads, dermal fillers, and skincare. He is a proud clinical trainer and lecturer at world-renowned Derma Medical academy – the UK’s number 1 aesthetics training provider; enabling him to share and teach his passion of aesthetics with other medical professionals.

Dr Nish is also the official trainer for Sunekos – provider of excellence in dermal biogenesis and winner of the Innovation and Pioneering Award at the Diamond Awards 2019.

At Medisha Clinic, you will always be treated by someone who is passionate about bringing their considerable knowledge and skills to bear to deliver the transformative, natural-looking results you are looking for.

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